Closing the Gap in HPV Pathogen Detection: A Simplicity™ Solution

Despite the advances of medicine, it is still the case that an estimated 2.2 million cancers worldwide are caused by infectious agents, with Human Papillomavirus (HPV) ranking as the second-leading cause among pathogen-driven cancers.¹

The CDC’s numbers paint a bleak picture of this preventable infection, showing HPV as responsible for²:

• 91% of cervical cancers
• 91% of anal cancers
• 63% of penile cancers
• 70% of oropharyngeal cancers

Despite widespread vaccination efforts, high-risk HPV types continue to affect more than 42 million Americans³, making research into how these genotypes circulate, persist, and differ more important than ever. Researchers need efficient tools to track and differentiate high-risk HPV genotypes.

Closing the Gap with Smarter PCR

Our new Human Papillomavirus (HPV) Simplicity Panel™ was designed to address workflow challenges seen in other PCR platforms. It includes targets for 14 high-risk HPV genotypes (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68) in the same pre-plated, breakaway format our customers rely on to streamline their workflows.

The Simplicity^TM Difference

Simplicity™ improves PCR workflows in several important ways:

• Minimized prep: our pre-plated, ready-to-use design eliminates reagent prep, reduces manual handling, and lowers the risk of errors.
• Short run time: the multiplex format covers all 14 high-risk genotype targets in a single run.

• Flexible batch processing: our 96-well breakaway format means you can maximize throughput efficiency—use only what you need, reduce unnecessary waste, and accommodate 
  variable sample volumes.

• Strict quality assurance: to ensure consistent reproducibility, all our panels are 
  manufactured to GMP and ISO 13485:2016 quality standards for research use only at our 
  US-based facility in Birmingham, Alabama.

These upgrades translate directly into impact: labs using our Simplicity™ format can see an 82% decrease in hands-on time. That’s more time back for your research. And every meaningful workflow improvement expands your lab’s ability to respond quickly and effectively when it matters most.

A Timely Tool for the Fight Against HPV

HPV remains one of the most prevalent viral infections in the U.S., yet many research laboratories lack the tools to track, study, and differentiate its high-risk genotypes efficiently. 

The Human Papillomavirus (HPV) Simplicity Panel™ can help laboratories of all sizes generate meaningful, reliable data that supports the ongoing fight against HPV-related diseases through research. 

References

1. de Martel C, Georges D, Bray F, Ferlay J, Clifford GM. Global burden of cancer attributable to infections in 2018: a worldwide incidence analysis. Lancet Glob Health. 2020 Feb;8(2):e180-e190. doi: 10.1016/S2214-109X(19)30488-7. Epub 2019 Dec 17. PMID: 31862245.
2. Chapter 11: Human papillomavirus. Epidemiology and Prevention of Vaccine-Preventable Diseases. Published April 23, 2024. https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-11-human-papillomavirus.html
3. About HPV. Human Papillomavirus (HPV). Published July 3, 2024. https://www.cdc.gov/hpv/about/index.html